The community-based PREVEND cohort (www.prevend.org) is an observational follow-up study (started in 1997), including 8592 individuals from the city of Groningen. The baseline screening program consisted of 2 outpatient visits to assess demographic factors, anthropometric measurements, cardiovasclar and metabolic risk factors, and health behavior and to collect blood samples and two 24-h urine samples on two consecutive days.
Participants were seen at 3-year intervals in the PREVEND outpatient clinic. Over 10 years of follow-up and data on cardiovascular morbidity and mortality, including atrial fibrillation is available. Within PREVEND, Rienstra focuses on cardiovascular risk factors, genetics, and atrial fibrillation.
The Northern Netherlands community-based Lifelines cohort (www.lifelines.nl) is an observational follow-up study (started in 2007), including >165,000 individuals covering three generations. Each participant has been extensively phenotyped at baseline, and will be followed for at least 30 years at 5-year intervals. Follow-up on morbidity and mortality are based on general practitioners, hospital and pharmacy records. Within Lifelines, Rienstra focuses on cardiovascular risk factors, genetics, ECG, and atrial fibrillation.